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Waikato DHB Palliative Care Guidelines

8. Excessive secretions

  • Can be a symptom in advanced respiratory disease, head and neck cancers and neuro-degenerative disorders.
  • In people who are dying, this may be part of the terminal process known as “Death Rattle”.
  • Explanation and reassurance for the patient and family is very helpful.
  • Suctioning should be avoided.
  • Re-positioning is often helpful .
  • Attention to oral hygiene is essential – see chapter 10.
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Drug therapy may be indicated but drying of secretions is not always the most appropriate initial management.

When considering the appropriate drug therapy, note the following:
  • Buscopandoes not cross the blood-brain barrier and therefore causes less sedation and confusion than Hyoscine hydrobromide and Scopoderm TTS™
  • Atropine is excitatory and should be avoided.
Hyoscine butylbromide (Buscopan™)
  • 20-40mg subcut 2-4 hourly.
  • 60 -120mg/ 24 hours subcut infusion.
  • Better tolerated in the unconscious or semi-conscious patient.
Hyoscine hydrobromide
  • 0.2-0.4mg subcut 2-4 hourly.
  • 0.6 -1.2mg/ 24 hours subcut infusion.
  • Recommended for use in the unconscious or semi-conscious patient.


Information last reviewed: June 2009
Please foward any enquiries about this document to
 haggars@waikatodhb.govt.nz
Next review date: July 2010 For Palliative Care advice, please call 8691 or the specialist on-call.

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Page last updated on 4/12/2009